Crosslinking Reagents
Sigma Organic Chemistry SMCC CONJUGATION KIT FOR IRON OXIDE (II III) NANOPARTICLES 20 NM AMINE FUNCTIONALIZED 5 MG/ML | 1KT
SMCC CONJUGATION KIT FOR IRON OXIDE (II III) NANOPARTICLES 20 NM AMINE FUNCTIONALIZED 5 MG/ML, 1KT
About This Item:
UNSPSC Code: 12352302
Storage: COOLER/REFRIGERATED
Sigma Organic Chemistry EDC CONJUGAITON KIT FOR IRON OXIDE (II III) NANOPARTICLES 30 NM CARBOXYLIC ACID FUNCTIONALIZED 5 MG/ML | 1KT
EDC CONJUGAITON KIT FOR IRON OXIDE (II III) NANOPARTICLES 30 NM CARBOXYLIC ACID FUNCTIONALIZED 5 MG/ML, 1KT
About This Item:
UNSPSC Code: 12352302
Storage: COOLER/REFRIGERATED
Sigma Organic Chemistry SMCC CONJUGATION KIT FOR IRON OXIDE (II III) NANOPARTICLES 30 NM AMINE FUNCTIONALIZED 5 MG/ML | 1KT
SMCC CONJUGATION KIT FOR IRON OXIDE (II III) NANOPARTICLES 30 NM AMINE FUNCTIONALIZED 5 MG/ML, 1KT
About This Item:
UNSPSC Code: 12352302
Storage: COOLER/REFRIGERATED
Cayman Chemical EZ-DroloxIfen 50mg
An acylhydrazone antifungal active against C. neoformans in vitro (MIC80 0.06 g/ml) increases survival in mouse models of C. neoformans C. albicans or A. fumigatus infection at 20 mg/kg per day p.o.
Cayman Chemical DIsuccInImIdyl Suberate 500mg
A potent inhibitor of DGAT-1 (IC50s 7 and 24 nM for human and mouse respectively) confers significant weight loss within seven days and significantly reduces plasma and liver triglycerides when administered at 3 mg/kg to DIO mice
Cayman Chemical CInabarInIc AcId 50mg
Pnolenc acd s a PUFA found n Korean pne (Pnus orentals) and martme pne (Pnus pnaster) seed ols Both ols have been found to have lpd-lowerng propertes A det contanng martme pne seed ol (MPSO) lowered HDL and ApoA1 levels n transgenc mce expressng human ApoA1 MPSO was found to dmnsh cholesterol efflux n vtro 14273 Korean pne seed ol supplements may help n obesty by reducton of appette People takng ths ol had an ncrease n the satety hormones CCK and GLP-1 and a reduced desre to eat 14280 The actvty of the ol s attrbuted to pnolenc acd Pnolenc acd s not converted to arachdonc acd metabolcally and can reduce arachdonc acd levels n the phosphatdylnostol fracton of Hep-G2 cells from 15 9 to 7 0 8724
Cayman Chemical Clobetasol PropIonate 5g
A pan-Akt inhibitor (IC50s 0 08 2 and 2 6 nM for Akt1 -2 and -3 respectively) selective for Akt over a panel of 13 kinases (IC50s 100 nM) but does inhibit PKA PKG1a and PKG1B (IC50s 1 3 0 9 and 4 nM respectively) inhibits tumor growth in an SKOV3 mouse xenograft model at 10 30 and 100 mg/kg
Cayman Chemical VulpInIc AcId 50mg
Contains the intermediary and secondary metabolites of PGE2 PGD2 and PGF2a designed for direct use in LC-MS applications
Cayman Chemical SuccInImIdyl 4formylbenzoate
Immunogen Phosphopeptide corresponding to amino acid residues surrounding phospho-Thr53 of rat DAT Host Rabbit Species Reactivity ( ) Mouse Rat Application WB MW 55 kDa
Cayman Chemical 12-keto LIthocholIc AcId 50mg
A prodrug form of VRT-043198 inhibits LPS-induced increases in serum IL-1B levels in mice at 50 100 and 200 mg/kg reduces oxazolone-induced ear edema and levels of IL-1B IL-18 and IFN-Y in ear tissue in an oxazolone-sensitized mouse model of delayed-type hypersensitivity reduces forepaw inflammation in a mouse model of collagen-induced arthritis in a dose-dependent manner decreases seizure duration and the number of seizures in a mouse model of acute seizures induced by hippocampal kainic acid injection at 50 mg/kg as well as delays the onset of seizures at 100 and 200 mg/kg reduces the aggregated duration of epileptic activity in a mouse model of chronic epilepsy
Cayman Chemical DIsuccInImIdyl Glutarate 25mg
A dual inhibitor of EGFR and HER2 (IC50s 92 and 59 nM respectively) selective for EGFR and HER2 over a panel of 12 kinases (IC50s 5000 nM) but does inhibit VEGFR2 and Src (IC50s 800 and 1400 nM respectively) inhibits the proliferation of NCI H508 colorectal cancer cells expressing wild-type or mutant forms of HER2 (IC50s 0 2-3 nM) reduces tumor growth in BT474 breast and SKOV3 ovarian cancer mouse xenograft models at 40 mg/kg
Cayman Chemical Sulfo-SMCCsodIum salt 100mg
A peptide agonist of GnRH binds to GnRHR (Ki 0 1 nM) decreases testicular volume semen volume sperm motility and total sperm count as well as increases the percentage of abnormal sperm in dogs via a subcutaneous implant at 3 6 and 12 mg per animal decreases disease severity and plasma levels of estradiol 17-hydroxyprogesterone and androstenedione in ferrets with ACD at 3 mg/implant per animal suppresses ovulation and estrus in cats at 4 7 mg/implant per animal
Cayman Chemical OlIvetolIc AcId 50mg
A non-selective inhibitor of CaCCs blocks ATP-stimulated chloride conductance in human salivary gland intestinal and bronchial epithelial cells (mean IC50 10 UM) induces full vasorelaxation of preconstricted mouse isolated mesenteric arteries in the presence or absence of chloride attenuates CaCC TMEM16-A-induced proliferation in cancer cell lines reduces KCa1.1/BK channel activity in human red blood cells
Cayman Chemical ArtemIsInIc AcId 50mg
An agonist of RAR isoforms (EC50s 77 35 and 4 nM for RARa RARa and RARY respectively) induces growth arrest of MCF-7 and NB4 cells in vitro a natural metabolite of vitamin A
Cayman Chemical SulfosuccInImIdyl 32 BIot 25mg
An inhibitor of the USP1-UAF complex (IC50 0.544 UM for its deubiquitinase activity) and SARS-CoV-2 PLpro (IC50s 0.56 and 0.091 UM using Z-LRGG-AMC or Ub-AMC respectively as PLpro substrates) reduces the levels of USP1 ID-1 ID-2 and ID-3 in K562 cells at 0.5-10 UM decreases the viability of K562 cells (EC50 1.07 UM) induces apoptosis in K562 cells in a concentration-dependent manner